Transcriptional control of regulatory T cell development and function
نویسندگان
چکیده
منابع مشابه
Transcriptional control of regulatory T-cell differentiation.
Regulatory T (Treg) cells are essential for maintaining peripheral tolerance and for limiting excessive inflammatory responses under various conditions. The lineage-specific transcription factor Foxp3 has a critical role in Treg-cell biology. Foxp3 forms large protein complexes and cooperates with environmentally induced transcription factors to shape the Treg-cell transcriptional program. Here...
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ژورنال
عنوان ژورنال: Trends in Immunology
سال: 2013
ISSN: 1471-4906
DOI: 10.1016/j.it.2013.08.003